Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioplastics01:27

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Filamentation-assisted isolated attosecond pulse generation.

Nature communications·2026
Same author

Circularly Polarized High-Harmonic Beams Carrying Self-Torque or Time-Dependent Orbital Angular Momentum.

ACS photonics·2024
Same author

Isolated attosecond pulse generation in a semi-infinite gas cell driven by time-gated phase matching.

Light, science & applications·2024
Same author

Polyhydroxy-3-Butyrate (PHB)-Based Composite Materials Reinforced with Cellulosic Fibers, Obtained from Barley Waste Straw, to Produce Pieces for Agriculture Applications: Production, Characterization and Scale-Up Analysis.

Materials (Basel, Switzerland)·2024
Same author

Robust Isolated Attosecond Pulse Generation with Self-Compressed Subcycle Drivers from Hollow Capillary Fibers.

ACS photonics·2024
Same author

A Comprehensive Study on the Effect of Plasticizers on the Characteristics of Polymer Inclusion Membranes (PIMs): Exploring Butyl Stearate as a Promising Alternative.

Membranes·2024
Same journal

Precision Nanotechnology in Oral Oncology: From Biomarker-Guided Targeting to AI-Driven Theranostics.

Current pharmaceutical design·2026
Same journal

Pharmacological Insights into Medicinal Plants and Phytomolecules for the Management of Alopecia with Mechanistic Perspectives and Therapeutic Potential.

Current pharmaceutical design·2026
Same journal

Addressing Challenges, Regulatory Shifts, and the Need for Cost-Effective Alternatives for Complex Topical Formulations.

Current pharmaceutical design·2026
Same journal

The Mechanism of Huaiqihuang in the Treatment of Nephrotic Syndrome: An Integrated Study Based on Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and Experimental Validation.

Current pharmaceutical design·2026
Same journal

Resveratrol and the NLRP3 Inflammasome: Unlocking the Anti-inflammatory Potential of a Natural Compound.

Current pharmaceutical design·2026
Same journal

The Use of Hemostatic Agents in Traumatic Bleeding: One Size Does Not Fit All.

Current pharmaceutical design·2026
See all related articles

Related Experiment Video

Updated: May 23, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Bioresorbable and nonresorbable polymers for bone tissue engineering.

Jordi Girones Molera1, José Alberto Mendez, Julio San Roman

  • 1Polymeric Nanomaterials and Biomaterials, Instituto de Ciencia y Tecnología de Polímeros, Consejo Superior de Investigaciones Científicas, Madrid, Spain. jgirones@ictp.csic.es

Current Pharmaceutical Design
|April 20, 2012
PubMed
Summary
This summary is machine-generated.

Bone tissue engineering offers advanced solutions for critical-sized bone defects, addressing rising age-related conditions. This review explores novel materials and strategies for bone regeneration, enhancing regenerative medicine.

More Related Videos

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
09:37

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

Related Experiment Videos

Last Updated: May 23, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
09:37

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

Area of Science:

  • Regenerative biomedicine
  • Biomaterials science
  • Orthopedic research

Background:

  • Increasing life expectancy leads to a rise in age-related diseases requiring bone repair.
  • Critical-sized bone defects often exceed the natural self-regeneration capacity of bone tissue.
  • Conventional bone grafts have limitations, necessitating alternative regenerative approaches.

Purpose of the Study:

  • To provide a comprehensive overview of bone tissue engineering.
  • To highlight recent advances in materials, techniques, and strategies for bone repair and regeneration.
  • To serve as a foundational resource for understanding current developments in the field.

Main Methods:

  • Literature review of recent publications in bone tissue engineering.
  • Synthesis of information on materials, techniques, and strategies.
  • Identification and discussion of key advancements and emerging trends.

Main Results:

  • Bone tissue engineering is a rapidly advancing field within regenerative medicine.
  • Novel materials and innovative strategies are continuously being developed for bone regeneration.
  • The review consolidates current knowledge on various aspects of bone tissue engineering.

Conclusions:

  • Bone tissue engineering presents a promising alternative to traditional bone grafting methods.
  • Continued research into new materials and strategies is crucial for improving bone defect treatment.
  • This field holds significant potential for addressing the challenges of bone repair and regeneration in an aging population.