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Related Concept Videos

Ultrasonography01:17

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...

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Updated: May 23, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
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Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

Ultrasonography in gout: a case-control study.

Sébastien Ottaviani1, Pascal Richette, Anne Allard

  • 1Université Paris Diderot, Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Fédération de Rhumatologie, Paris, France. sebastien.ottaviani@bch.aphp.fr

Clinical and Experimental Rheumatology
|April 20, 2012
PubMed
Summary
This summary is machine-generated.

Ultrasonography effectively diagnoses gout, showing high sensitivity and specificity for the double contour sign and tophi. Diagnostic accuracy varies by joint location and disease severity, aiding in gout assessment.

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Area of Science:

  • Rheumatology
  • Medical Imaging
  • Diagnostic Accuracy

Background:

  • Gout is a common inflammatory arthritis characterized by hyperuricemia and urate crystal deposition.
  • Accurate diagnosis of gout is crucial for effective management and preventing joint damage.
  • Ultrasonography is increasingly used to visualize MSU crystal deposition and associated features of gout.

Purpose of the Study:

  • To evaluate the sensitivity and specificity of ultrasonography in diagnosing gout.
  • To explore the correlation between ultrasonographic findings and gout severity.

Main Methods:

  • A case-control study involving 53 patients with crystal-proven gout and 50 controls.
  • Prospective ultrasonographic examination of 10 specific joints per participant.
  • Assessment for the presence of the double contour (DC) sign and tophi at each joint site.

Main Results:

  • Ultrasonography demonstrated high specificity (>98%) for the DC sign and 100% for tophi.
  • Sensitivity for the DC sign varied by joint: MTPs (67%), knees (57%), MCPs (21%).
  • Tophi sensitivity was 74% (MTPs), 42% (knees), and 22% (MCPs); the DC sign correlated with uricemia and disease duration.

Conclusions:

  • Ultrasonography is a sensitive and specific tool for diagnosing gout.
  • The diagnostic sensitivity of ultrasonography for gout is influenced by the joint examined, disease duration, and overall disease severity.