Heart failure survival score in patients with Chagas disease: correlation with functional variables

Luiz E Ritt1, Antonio Carlos Carvalho, Gilson S Feitosa

  • 1Departamento de Cardiologia, Universidade Federal de São Paulo, São Paulo, Brazil.

Insights

The Heart Failure Survival Score effectively predicts outcomes in patients with Chagas disease-related heart failure. This score correlates well with key functional tests, offering valuable prognostic insights for this population.

Area of Science:

  • Cardiology
  • Tropical Medicine
  • Public Health

Background:

  • Chagas disease is a significant cause of heart failure in Latin America with a poorer prognosis than other etiologies.
  • The Heart Failure Survival Score is established for heart failure prognosis but unstudied in Chagas cardiopathy.

Purpose of the Study:

  • To evaluate the Heart Failure Survival Score's correlation with functional parameters in patients with Chagas cardiopathy.

Main Methods:

  • Calculated the Heart Failure Survival Score in 55 patients with severe left ventricular systolic dysfunction due to Chagas disease.
  • Assessed correlations between the score and cardiopulmonary exercise tests, quality of life, and 6-minute walking tests.

Main Results:

  • The Heart Failure Survival Score showed strong correlations with peak oxygen uptake, anaerobic threshold, ventilation carbon dioxide efficiency, and 6-minute walking test distance.
  • Significant correlations were also observed with left ventricle ejection fraction and left atrium diameter.

Conclusions:

  • The Heart Failure Survival Score is a valuable tool for assessing prognosis in heart failure patients with Chagas disease.
  • The score's strong correlation with functional test variables supports its utility in clinical practice for this population.
Abstract

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