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Updated: Aug 11, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[Clinical radiobiology of fast electrons]
1Divisione di Radioterapia Oncologica, Università degli Studi La Sapienza, Roma.
Abstract:
The characteristics of microdosimetry, in terms of "lineal energy" value distribution, differ widely between high energy photons and electrons, so as to explain the existence of measurable RBE differences. Nevertheless one can accept for clinical purposes the RBE value 0.9 and a correlated dose increment of 10%. Most important are the macrodosimetric features of electron beams. As far as the skin reactions are concerned, they depend on many factors and are gaining a new relevance in clinical radiotherapy, being a guide in the treatment policy for a given patient.
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