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Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...

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Related Experiment Video

Updated: May 23, 2026

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
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Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model

Published on: July 1, 2018

Streptococcus suis meningitis: First case reported in Quebec.

S Michaud1, R Duperval, R Higgins

  • 1Département de médecine, Faculté de médecine, Université de Sherbrooke, Sherbrooke, Québec and Faculté de médecine vétérinaire, Groupe de recherche sur les maladies infectieuses du porc, Université de Montréal, Montréal, Québec.

The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses
|April 20, 2012
PubMed
Summary
This summary is machine-generated.

Streptococcus suis infections, though common in pigs, are rarely reported in humans in Canada. This occupational illness, causing meningitis and hearing loss, may be underdiagnosed in swine workers.

Keywords:
Streptococcus suisSwine workers meningitisZoonosis

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Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
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Area of Science:

  • Veterinary Medicine
  • Infectious Diseases
  • Public Health

Background:

  • Streptococcus suis is a significant pathogen in swine populations globally.
  • Human infections with S. suis are uncommon but can lead to severe clinical outcomes, including meningitis.
  • Occupational exposure is the primary route for human S. suis transmission, particularly for individuals working closely with pigs.

Observation:

  • Meningitis is the most frequent clinical presentation of S. suis infection in humans.
  • Hearing loss is a common and potentially severe sequela of S. suis meningitis.
  • The bacterium may be misidentified, leading to underdiagnosis of S. suis infections in clinical settings.

Findings:

  • This report details the first case of S. suis type 2 meningitis identified in Quebec, Canada.
  • The case occurred in a swine worker, highlighting the occupational nature of the disease.
  • The diagnosis was confirmed through microbiological identification.

Implications:

  • Physicians and microbiologists in Quebec should maintain a high index of suspicion for S. suis meningitis in swine workers.
  • Increased awareness is crucial for accurate diagnosis and timely management of S. suis infections in at-risk populations.
  • Enhanced surveillance and diagnostic protocols may be necessary to address potential underreporting of this zoonotic disease.