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Updated: May 23, 2026

Listeria monocytogenes Infection of the Brain
Published on: October 2, 2018
Rhomboencephalitis caused by Listeria monocytogenes
1Division of General Internal Medicine, Victoria General Hospital; and Faculty of Medicine, University of Dalhousie, Halifax, Nova Scotia.
Abstract:
Listerial rhomboencephalitis is a rare, devastating treatable disease. A previously well 72-year-old man presented with a one-week history of fever and headache. Four days before admission he developed right facial numbness and ataxia. Diagnosis and treatment are described, including the relevant clinical, laboratory and radiological findings.
Insights
Listerial rhomboencephalitis, a rare but treatable neurological disease, can present with fever, headache, and ataxia. Early diagnosis and treatment are crucial for managing this devastating condition.
Area of Science:
- Neurology
- Infectious Diseases
- Neuroscience
Background:
- Listerial rhomboencephalitis is a rare central nervous system infection caused by Listeria monocytogenes.
- The disease can lead to severe neurological deficits if not promptly treated.
Observation:
- A previously healthy 72-year-old male presented with a week of fever and headache.
- Symptoms progressed to include right-sided facial numbness and ataxia.
Findings:
- The case highlights key clinical, laboratory, and radiological findings for diagnosing listerial rhomboencephalitis.
- Diagnostic confirmation relies on a combination of clinical suspicion and specific tests.
Implications:
- This case underscores the importance of considering listerial rhomboencephalitis in patients with compatible neurological symptoms.
- Timely diagnosis and appropriate antibiotic therapy are essential for favorable outcomes.
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