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Updated: May 23, 2026

Assay Development for High-Throughput Drug Screening Against Mycobacteria
Published on: October 25, 2024
Short course monotherapy with clarithromycin for localized Mycobacterium marinum skin infection
M R Weinstein1, D E Low, T Mazzulli
1Department of Microbiology, Mount Sinai Hospital and University of Toronto, Toronto, Ontario.
Abstract:
In vitro studies have shown that Mycobacterium marinum is usually susceptible to clarithromycin. However, there are limited published data on the clinical use of clarithromycin for the treatment of M marinum infections. This report describes a previously healthy 58-year-old man who developed a chronic soft tissue infection of his right hand caused by M marinum. He responded to four weeks' therapy with clarithromycin. Follow-up at six months showed no relapse. Our experience and review of the literature suggest that short course monotherapy with clarithromycin may be quite effective for uncomplicated soft issue infections caused by M marinum.
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