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Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: May 23, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Atrophic dermatofibrosarcoma protuberans.

Ola Bakry1, Abdalla Attia

  • 1Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt.

Journal of Dermatological Case Reports
|April 20, 2012
PubMed
Summary
This summary is machine-generated.

Atrophic dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing skin cancer. Complete surgical excision and long-term follow-up are crucial for managing this low-to-moderate grade malignancy and preventing recurrence.

Keywords:
CD34Moh's micrographic surgeryatrophic plaquedermatofibrosarcoma protuberanssarcoma

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Area of Science:

  • Dermatopathology
  • Oncology
  • Surgical Oncology

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is a rare dermal mesenchymal tumor.
  • Atrophic DFSP, a rare variant, mimics benign skin conditions like morphea.
  • DFSP exhibits slow infiltrative growth and a high recurrence rate if not fully excised.

Observation:

  • A case of atrophic DFSP in a 52-year-old female is presented.
  • Diagnosis was confirmed through clinical, histopathological, and immunohistochemical analysis.
  • The tumor was treated with surgical excision and is under ongoing follow-up.

Findings:

  • Atrophic DFSP is a low to moderate grade malignancy.
  • Complete surgical excision with adequate margins is the primary treatment.
  • Recurrence is common if excision is incomplete, with rare metastasis after repeated recurrence.

Implications:

  • Early and accurate diagnosis of atrophic DFSP is essential.
  • Surgical management is critical for optimal patient outcomes.
  • Long-term surveillance is necessary to monitor for potential recurrence.