[Breast cancer and the background processes]

A morphologic study of the background changes in mammary tissue was carried out, based on systematization of elementary, nosologically and morphologically well determined parenchymatous structures with the use of analysis of correlations. Regularities in the relationships between parenchymatous changes were revealed, depending on the site and severity of epithelial dysplasia. Statistical analysis has proved that grave epithelial dysplasia is a marker of high risk of preinvasive and invasive carcinoma. Histologic structure of both invasive and preinvasive carcinoma is not always determined by the site of grave epithelial dysplasia in certain type structures. Regularities in relationships and combinations of parenchymatous structures associated with severe epithelial dysplasia are diagnostically valuable for the detection of preinvasive and invasive carcinoma irrespective of its histologic form.