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Updated: May 23, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
The many faces of nickel allergy
Razvigor Darlenski1, Jana Kazandjieva, Kyrill Pramatarov
1Department of Dermatology and Venereology, Tokuda Hospital, Bulgaria. darlenski@abv.bg
Abstract:
Hypersensitivity reactions to nickel are one of the most common in the modern world. Nickel allergy prevalence is constantly growing in many countries and represents a major health and socioeconomic issue. Herein the current understanding on nickel allergy is summarized with a practical approach to the dermatologist, allergist, and general practitioner. The personal experience with some practical clinical cases of nickel dermatitis is shared. A special emphasis is put on the possible strategies for treatment and prevention of the disease.
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