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Acitretin in management of diffuse common warts: a case report
Ilaria Proietti1, Nevena Skroza, Nicoletta Bernardini
1Department of Dermatology "Daniele Innocenzi," University of Rome "Sapienza," Polo Pontino, Italy.
Dermatologic Therapy
|April 21, 2012
Summary
Common warts, caused by human papilloma virus (HPV), can be aggressive. Acitretin therapy effectively resolved extensive common warts (HPV4) in an immunocompetent patient.
Area of Science:
- Dermatology
- Virology
Background:
- Warts are common skin conditions caused by human papilloma virus (HPV).
- Therapeutic approaches vary based on lesion severity and extent.
- HPV subtypes 1-2 are most common; HPV 4-7 are rarer, often linked to occupational exposure.
Observation:
- A 32-year-old immunocompetent male presented with numerous exophytic papules on hands and periungual areas.
- Lesions appeared approximately 6 months prior to presentation.
- Histological examination confirmed common warts, specifically HPV type 4.
Findings:
- The patient received oral acitretin treatment for 12 weeks.
- Complete resolution of skin lesions was observed by the 8th week of therapy.
- This case highlights an unusual presentation of aggressive viral warts in an immunocompetent individual.
Implications:
- Acitretin demonstrates potential efficacy in treating aggressive common warts.
- This case expands treatment options for recalcitrant HPV infections.
- Further research may explore acitretin's role in managing severe wart cases.
