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Angiotensin-converting enzyme inhibitors in pregnancy may result in neonatal renal failure

S A Hulton1, P D Thomson, P A Cooper

  • 1Department of Paediatrics and Child Health, University of the Witwatersrand, Johannesburg Hospital.

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
|December 1, 1990
PubMed

Oligohydramnios and neonatal renal failure is reported in a premature infant whose mother had used enalapril in weeks 32-35 of her pregnancy. The infant recovered adequate renal function after peritoneal dialysis. Review of the literature supports our view that angiotensin-converting enzyme inhibitors should not be used in pregnancy; if they are, both mother and fetus should be monitored with extreme care.

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