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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: May 23, 2026

Optimized Minimally Invasive Transscleral Subretinal Injection Technique in Mouse
06:46

Optimized Minimally Invasive Transscleral Subretinal Injection Technique in Mouse

Published on: July 25, 2025

Mini-drainage devices: the Ex-PRESS Mini-Glaucoma Device.

J Matthew Rouse1, Steven R Sarkisian

  • 1Dean .McGee Eye Institute, Department of Ophthalmology, University of Oklahoma College of Medicine, Oklahoma City, Okla., USA.

Developments in Ophthalmology
|April 21, 2012
PubMed
Summary
This summary is machine-generated.

The Ex-PRESS Mini-Glaucoma Device effectively lowers intraocular pressure by shunting aqueous humor. This review analyzes its surgical applications, benefits, and drawbacks in glaucoma management.

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Last Updated: May 23, 2026

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Published on: February 15, 2022

Area of Science:

  • Ophthalmology
  • Microsurgery
  • Medical Devices

Background:

  • Glaucoma is a leading cause of irreversible blindness worldwide.
  • Elevated intraocular pressure (IOP) is a primary risk factor for glaucoma progression.
  • The Ex-PRESS Mini-Glaucoma Device is a widely used implant for IOP reduction.

Purpose of the Study:

  • To review the surgical uses, techniques, and considerations for the Ex-PRESS Mini-Glaucoma Device.
  • To analyze the current literature on the advantages and disadvantages of the Ex-PRESS implant.
  • To present the authors' experience with the Ex-PRESS device.

Main Methods:

  • Literature review of studies on the Ex-PRESS Mini-Glaucoma Device.
  • Analysis of surgical techniques and patient outcomes.
  • Synthesis of clinical experience and published data.

Main Results:

  • The Ex-PRESS device has been successfully implanted in approximately 60,000 cases globally.
  • The device functions by shunting aqueous humor to a subconjunctival reservoir.
  • Current literature highlights both benefits and potential complications associated with its use.

Conclusions:

  • The Ex-PRESS Mini-Glaucoma Device represents advanced technology in IOP-lowering surgical options.
  • A comprehensive understanding of its surgical application, benefits, and risks is crucial for optimal patient care.
  • Further analysis of the authors' experience will contribute to the existing body of knowledge.