Related Experiment Video
Updated: May 23, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Patient preferences for coronary artery bypass graft surgery or percutaneous intervention in multivessel coronary
Ryan Kipp1, James Lehman, Jacqueline Israel
1Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Insights
Patients with multivessel coronary artery disease (mv-CAD) prefer percutaneous coronary intervention (mv-PCI) over coronary artery bypass graft surgery (CABG), even with higher risks. Physicians showed greater risk aversion than patients when choosing between mv-PCI and CABG.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiovascular Surgery
Background:
- Patient risk perception and treatment preferences for multivessel coronary artery disease (mv-CAD) remain unclear.
- Understanding these preferences is crucial for shared decision-making in revascularization strategies.
Purpose of the Study:
- To determine patient preference between multivessel percutaneous coronary intervention (mv-PCI) and coronary artery bypass graft surgery (CABG) for symptomatic mv-CAD.
- To compare patient and physician preferences for these revascularization methods under varying risk scenarios.
Main Methods:
- A hypothetical scenario of medically refractory mv-CAD was presented to 585 patients and 31 physicians.
- Participants indicated their preferred treatment (mv-PCI or CABG) based on variable 1-year risks of death, stroke, and repeat procedures for mv-PCI versus fixed risks for CABG.
- Statistical analysis calculated the odds of favoring mv-PCI over CABG across different risk levels.
Main Results:
- Patients overwhelmingly preferred mv-PCI over CABG, even when mv-PCI carried double the risk of death or triple the risk of repeat procedures.
- Physicians were more risk-averse than patients, opting for CABG more frequently as the quoted risks for mv-PCI increased.
- Physician preference for mv-PCI decreased significantly with higher risks compared to patient preference.
Conclusions:
- Patients demonstrate a strong preference for mv-PCI over CABG for treating mv-CAD, irrespective of significantly higher associated risks.
- Physicians' treatment preferences are more closely aligned with objective risk assessment than patient preferences.
- This highlights a potential discordance between patient desires and physician-recommended strategies in mv-CAD management.
Objectives:
Determine if patients prefer multivessel percutaneous coronary intervention (mv-PCI) over coronary artery bypass graft surgery (CABG) for treatment of symptomatic multivessel coronary artery disease (mv-CAD) despite high 1-year risk.
Background:
Patient risk perception and preference for CABG or mv-PCI to treat medically refractory mv-CAD are poorly understood. We hypothesize that patients prefer mv-PCI instead of CABG even when quoted high mv-PCI risk.
Methods:
585 patients and 31 physicians were presented standardized questionnaires with a hypothetical scenario describing chest pain and medically refractory mv-CAD. CABG or mv-PCI was presented as treatment options. Risk scenarios included variable 1-year risks of death, stroke, and repeat procedures for mv-PCI and fixed risks for CABG. Participants indicated their preference of revascularization method based on the presented risks. We calculated the odds that patients or physicians would favor mv-PCI over CABG across a range of quoted risks of death, stroke, and repeat procedures.
Results:
For nearly all quoted risks, patients preferred mv-PCI over CABG, even when the risk of death was double the risk with CABG or the risk of repeat procedures was more than three times that for CABG (P < 0.0001). Compared to patients, physicians chose mv-PCI less often than CABG as the risk of death and repeat procedures increased (P < 0.001 and P = 0.004, respectively).
Conclusion:
Patients favor mv-PCI over CABG to treat mv-CAD, even if 1-year risks of death and repeat procedures far exceed risk with CABG. Physicians are more influenced by actual risk and prefer mv-PCI less than patients despite similarly quoted 1-year risks.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management
Angina IV: Management
Acute Coronary Syndrome IV: Interprofessional Care
Cardiac Catheterization I: Pre-Procedure Overview
