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Updated: May 23, 2026

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Comprehensive Echocardiographic Assessment of Right Ventricle Function in a Rat Model of Pulmonary Arterial Hypertension
Published on: January 20, 2023
Are right ventricular risk scores useful?
Matteo Pettinari1, Steven Jacobs, Filip Rega
1Department of Cardiac Surgery, University Hospital Leuven, Leuven, Belgium. matteo.pettinari@uzleuven.be
Summary
Risk scores failed to predict right ventricular (RV) failure after left ventricular assist device (LVAD) implantation. High pulmonary vascular resistance and non-ischaemic cardiomyopathy were key predictors, urging caution when using existing scores.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Medical Devices
Background:
- Left ventricular assist device (LVAD) implantation is a critical treatment for advanced heart failure.
- Right ventricular (RV) failure is a significant complication following LVAD implantation.
- Predictive scores for RV failure after LVAD exist but require validation.
Purpose of the Study:
- To validate three established risk scores for predicting RV failure in patients receiving rotary blood pump LVADs.
- To identify independent predictors of RV support need post-LVAD implantation.
Main Methods:
- Retrospective analysis of preoperative data (clinical, echocardiographic, laboratory, hemodynamic) from 59 LVAD implantations.
- Calculation of three previously published predictive scores for all patients.
- Logistic regression analysis to determine predictors of RV support.
Main Results:
- Twenty-three point seven percent of patients required additional temporary RV support.
- The three validated scores did not significantly differ between groups and were not predictive of RV failure.
- High pulmonary vascular resistance and non-ischaemic cardiomyopathy were identified as significant predictors of RV support need.
Conclusions:
- Current risk scores are inadequate for predicting RV support requirements after LVAD implantation.
- Clinical judgment should be prioritized, and existing scores used with extreme caution for risk stratification.
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