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Updated: May 23, 2026

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
Published on: October 12, 2016
Use of allogenous bone graft and osteosynthetic stabilization in treatment of massive post-sternotomy defects
Martin Kalab1, Martin Molitor, Barbara Kubesova
1Department of Cardiac Surgery, University Hospital and Faculty of Medicine, Palacky University, Olomouc, Czech Republic. martin.kalab@email.cz
Abstract:
Thoracic stabilization using transverse plate fixation represents a modern and safe method of sternal dehiscence treatment. However, it still remains difficult to apply in cases of massive loss of bone tissue of the chest wall. An unsatisfactory stability of thorax often results in severe respiratory insufficiency, and also affects healing of soft tissue closure while increasing the risk of development of chronic fistulas and other dehiscences. In the reported case, we opted for a unique treatment of massive post-sternotomy defect using an allogenous bone graft of calva. Transverse titanium plates were applied to achieve stabilization of bone grafts and chest wall.
