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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
A review of risk factors for stroke in patients with chronic kidney disease
Fahad Saeed1, Nadia Kousar, Kamran Qureshi
1Departments of Internal Medicine (FS, NK, KQ) and Neurology (TNL), Univerity of Illinois School of Medicine, Urbana Champaign, IL.
Insights
Patients with chronic kidney disease (CKD) face increased stroke risk due to numerous cardiovascular factors. Identifying and addressing these risks early is crucial for reducing stroke incidence and mortality in CKD patients.
Area of Science:
- Nephrology
- Neurology
- Cardiovascular Medicine
Background:
- Patients with chronic kidney disease (CKD) exhibit a higher prevalence of traditional and non-traditional cardiovascular risk factors.
- This elevated risk profile predisposes individuals with CKD to a greater likelihood of experiencing stroke events.
Purpose of the Study:
- To review and summarize existing literature on risk factors for stroke in patients diagnosed with chronic kidney disease.
- To identify key factors contributing to stroke incidence and mortality within the CKD population.
Main Methods:
- An extensive literature review was conducted using a predefined set of keywords.
- The review focused on studies that evaluated predisposing risk factors for stroke specifically in patients with CKD.
Main Results:
- The incidence of stroke and associated mortality are significantly higher in CKD patients compared to the general population.
- Specific factors such as anemia, hypoalbuminemia, malnutrition, uremia, and hyperhomocysteinemia are linked to increased stroke risk in CKD.
- Patients undergoing hemodialysis or renal transplantation face a higher risk of stroke than those not requiring renal replacement therapy.
Conclusions:
- Early identification of stroke risk factors in the CKD population is essential.
- Timely interventions targeting these identified risk factors hold the potential to decrease stroke incidence and mortality rates.
Background:
Patients with chronic kidney disease (CKD) are at higher risk for stroke because of higher prevalence of traditional and non-traditional cardiovascular risk factors.
Methods:
We performed an extensive literature review with pre-defined keywords. We summarized the results of the studies evaluating for risk factors predisposing to stroke in CKD patients.
Results:
The incidence of stroke and stroke-related mortality is higher in CKD patients compared with the general population. Presence of anemia, hypoalbuminemia, malnutrition, uremia, and hyperhomocysteinemia in patients with CKD is associated with higher incidence of stroke. Hemodialysis and renal transplant patients are at higher risk of developing stroke compared with those who do not require renal replacement therapy.
Conclusion:
The early recognition of risk factors associated with stroke in CKD population is imperative. Early interventions may potentially decrease the incidence and associated mortality of stroke in CKD patients.
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