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Updated: May 23, 2026

Development of a Neonatal Rat Model for Brachial Plexus Birth Injury
Published on: March 27, 2026
Risk factors at birth for permanent obstetric brachial plexus injury and associated osseous deformities
Rahul K Nath1, Nirupama Kumar, Meera B Avila
1Research Division, Texas Nerve and Paralysis Institute, Houston, TX 77030, USA.
Insights
Shoulder dystocia is the primary risk factor for permanent obstetric brachial plexus injury (OBPI). Forceps or vacuum-assisted delivery independently increases OBPI risk, irrespective of infant birth weight.
Area of Science:
- Obstetrics
- Neurology
- Pediatric Surgery
Background:
- Obstetric brachial plexus injury (OBPI) is a significant concern in childbirth.
- Identifying reliable predictors of OBPI is crucial for improved patient outcomes.
Purpose of the Study:
- To identify the most common risk factors associated with permanent obstetric brachial plexus injury (OBPI).
- To determine better predictors for OBPI development.
Main Methods:
- A population-based study involving 241 patients with OBPI who underwent surgical treatment.
- Analysis of risk factors including shoulder dystocia, birth weight, and mode of delivery.
Main Results:
- Shoulder dystocia was present in 97% of OBPI cases.
- Instrumental delivery (forceps/vacuum) was an independent risk factor, occurring at 41% compared to a 10% national rate.
- Birth weight, including macrosomia, was not a determining factor for OBPI prognosis.
Conclusions:
- Forceps/vacuum delivery is an independent risk factor for OBPI, unrelated to birth weight.
- Children with finger movement at birth exhibit more severe shoulder deformities compared to those without.
Abstract:
Purpose. To examine the most prevalent risk factors found in patients with permanent obstetric brachial plexus injury (OBPI) to identify better predictors of injury. Methods. A population-based study was performed on 241 OBPI patients who underwent surgical treatment at the Texas Nerve and Paralysis Institute. Results. Shoulder dystocia (97%) was the most prevalent risk factor. We found that 80% of the patients in this study were not macrosomic, and 43% weighed less than 4000 g at birth. The rate of instrument use was 41% , which is 4-fold higher than the 10% predicted for all vaginal deliveries in the United States. Posterior subluxation and glenoid version measurements in children with no finger movement at birth indicated a less severe shoulder deformity in comparison with those with finger movement. Conclusions. The average birth weight in this study was indistinguishable from the average birth weight reported for all brachial plexus injuries. Higher birth weight does not, therefore, affect the prognosis of brachial plexus injury. We found forceps/vacuum delivery to be an independent risk factor for OBPI, regardless of birth weight. Permanently injured patients with finger movement at birth develop more severe bony deformities of the shoulder than patients without finger movement.
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