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A rare case of perforated Meckel's diverticulum presenting as a gatrointestinal stromal tumor
1Kayseri Training and Research Hospital, Department of General Surgery, Kayseri, Turkey. selimsozen63@yahoo.com
Abstract:
Meckel's diverticulum is located on the antimesentric border of the ileum, approximately 45 to 60 cm proximal to the ileocecal valve, and results from incomplete closure of the omphalomesentric or viteline duct. Common complications presenting in adults include bleeding, obstruction, diverticulitis, and perforation. Tumors within Meckel's diverticulum are a rare, but recognized complication. A 62 year-old woman presented with peri-umbilical pain that had localized to the right iliac fossa. On examination, she was tender in the right iliac fossa, with localized peritonism. At surgery,a perforated Meckel's diverticulum was found that was associated with free intra-abdominal fluid and hemorrhage. A 25 mm nodule was found at the apex of Meckel's diverticulum. We resected 100 mm of the small bowel and a primary anastamosis was performed. Histopathological examination of the resected lesion revealed a mesenchymal tumor categorized as a gastrointestinal stromal tumor (GISTs). GISTs arising from Meckel's diverticulum are an extremely rare, but recognized complication. Surgery is considered the standard treatment for non-metastatic GISTs with enbloc resection and clear margins.
Insights
Gastrointestinal stromal tumors (GISTs) are a rare complication of Meckel's diverticulum. This case highlights surgical resection as the standard treatment for non-metastatic GISTs.
Area of Science:
- Gastroenterology
- Surgical Oncology
Background:
- Meckel's diverticulum, a congenital anomaly resulting from incomplete closure of the omphalomesenteric duct, is typically located on the antimesentric border of the ileum.
- While common complications include bleeding, obstruction, diverticulitis, and perforation, tumors are a rare occurrence.
Observation:
- A 62-year-old woman presented with abdominal pain, localized tenderness, and peritonism, indicative of a perforated Meckel's diverticulum.
- Surgical exploration revealed a perforated Meckel's diverticulum with associated intra-abdominal fluid and hemorrhage, along with a 25 mm nodule at its apex.
Findings:
- Histopathological examination of the resected lesion confirmed the presence of a gastrointestinal stromal tumor (GIST).
- Gastrointestinal stromal tumors arising from Meckel's diverticulum are an extremely rare complication.
Implications:
- Surgical resection with clear margins is the standard treatment for non-metastatic GISTs.
- This case underscores the importance of considering rare complications like GISTs in the differential diagnosis of Meckel's diverticulum presentations.
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