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Updated: Jan 20, 2026

Modeling Metastatic Endometrial Cancer Model: A Technique to Generate Endometrial Cancer with Lymph Node Metastasis in Rabbit Models
Published on: April 30, 2023
MicroRNAs and lymph node metastatic disease in lung cancer
Francesco Fazi1, Giulia Fontemaggi
1Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Corso della Repubblica 79, 04100 Latina, Italy. francesco.fazi@uniroma1.it
Abstract:
Lymphatic and distant metastases are primary factors in determining survival in patients with lung cancer. The identification of novel molecular biomarkers that can predict the presence of micrometastasis in lymph nodes and their incorporation in traditional histologic staging is needed. MicroRNAs are emerging as powerful biomarkers for several neoplastic disorders. This article reports the experimental results that have recently led to the identification of several microRNAs deregulated in lung cancer that are strongly associated with lymph node metastasis and advanced clinical stage. This evidence indicates that microRNAs are a promising tool for the clinical management of lung cancer.
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