Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anthelminthic Agents01:15

Anthelminthic Agents

Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A community-level complementary-food safety and hygiene intervention improves family-food preparation behaviours in rural Gambia: a follow-up of a cluster randomised controlled trial.

BMJ global health·2026
Same author

Impact on childhood mortality of interventions to improve drinking water, sanitation, and hygiene (WASH) to households: Systematic review and meta-analysis.

PLoS medicine·2023
Same author

PROTOCOL: Water, sanitation and hygiene for reducing childhood mortality in low- and middle-income countries.

Campbell systematic reviews·2023
Same author

PROTOCOL: Evidence and Gap Map Protocol: Interventions promoting safe water, sanitation, and hygiene for households, communities, schools, and health facilities in low- and middle-income countries.

Campbell systematic reviews·2023
Same author

Interventions promoting uptake of water, sanitation and hygiene (WASH) technologies in low- and middle-income countries: An evidence and gap map of effectiveness studies.

Campbell systematic reviews·2023
Same author

Protocol for a parallel group, two-arm, superiority cluster randomised trial to evaluate a community-level complementary-food safety and hygiene and nutrition intervention in Mali: the MaaCiwara study (version 1.3; 10 November 2022).

Trials·2023

Related Experiment Video

Updated: May 23, 2026

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
06:49

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians

Published on: March 14, 2014

Why is dracunculiasis eradication taking so long?

Sandy Cairncross1, Ahmed Tayeh, Andrew Seidu Korkor

  • 1London School of Hygiene & Tropical Medicine, Keppel St, London WC1E 7HT, UK. sandy.cairncross@lshtm.ac.uk

Trends in Parasitology
|April 24, 2012
PubMed
Summary
This summary is machine-generated.

Global eradication of Guinea worm disease (dracunculiasis) has faced significant delays due to insufficient or poorly utilized resources. Increased investment in Ghana dramatically accelerated eradication efforts, offering valuable lessons for future public health campaigns.

More Related Videos

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
08:48

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase

Published on: November 5, 2021

Mass Production of Genetically Modified Aedes aegypti for Field Releases in Brazil
17:41

Mass Production of Genetically Modified Aedes aegypti for Field Releases in Brazil

Published on: January 4, 2014

Related Experiment Videos

Last Updated: May 23, 2026

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
06:49

Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians

Published on: March 14, 2014

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
08:48

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase

Published on: November 5, 2021

Mass Production of Genetically Modified Aedes aegypti for Field Releases in Brazil
17:41

Mass Production of Genetically Modified Aedes aegypti for Field Releases in Brazil

Published on: January 4, 2014

Area of Science:

  • Global Health
  • Infectious Disease Control
  • Public Health Policy

Background:

  • Dracunculiasis, or Guinea worm disease, eradication efforts have significantly exceeded initial timelines.
  • Smallpox eradication was achieved in 10 years, contrasting with the protracted Guinea worm disease campaign.

Purpose of the Study:

  • To investigate the reasons behind the prolonged timeline for dracunculiasis eradication.
  • To identify factors contributing to the slow progress and stagnation of eradication programs.
  • To draw lessons from variable country-specific successes for future disease eradication initiatives.

Main Methods:

  • Analysis of historical data and program timelines for dracunculiasis eradication globally.
  • Case study examination of Guinea worm disease control programs, with a focus on Ghana's experience.
  • Comparative analysis of resource allocation and its impact on eradication success.

Main Results:

  • The primary reasons for delays in Guinea worm disease eradication are lack of resources and ineffective resource utilization.
  • Ghana's dracunculiasis program stagnated for a decade until increased resources were allocated in 2007.
  • Following resource enhancement in 2007, Guinea worm disease transmission in Ghana was interrupted within three years.

Conclusions:

  • Effective resource allocation and utilization are critical for the successful and timely eradication of infectious diseases.
  • The Ghana case study demonstrates that targeted and sufficient investment can rapidly overcome eradication challenges.
  • Lessons learned from dracunculiasis eradication are crucial for optimizing future global health initiatives and disease elimination strategies.