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Related Experiment Video

Updated: May 23, 2026

Catheterization of Intestinal Loops in Ruminants

Catheterization of Intestinal Loops in Ruminants

Published on: June 11, 2009

Acute phase proteins in ruminants.

F Ceciliani¹, J J Ceron, P D Eckersall

¹Department of Animal Pathology, Hygiene and Veterinary Public Health - University of Milano, Milano, Italy.

Journal of Proteomics

|April 24, 2012

Summary

Ruminant acute phase proteins (APP) are key indicators of infection and injury. This review details their structure, function, clinical use in veterinary diagnostics, and proteomic alterations in various ruminant species.

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Area of Science:

Veterinary Medicine
Biochemistry
Animal Science

Background:

Physiological responses to infection/injury involve inflammation and systemic acute phase reactions (APR).
APR includes fever, leukocytosis, and changes in Acute Phase Proteins (APP) in biological fluids.
Proteomics reveals significant alterations in APP during infection, with many being high-abundance proteins.

Purpose of the Study:

To review recent research on ruminant Acute Phase Proteins (APP).
To cover APP structure, function, and regulation in ruminants.
To discuss clinical applications and proteomic findings related to ruminant APP.

Main Methods:

Review of recent scientific literature on ruminant APP.
Analysis of proteomic data investigating APP alterations.
Synthesis of information on APP structure, function, regulation, and clinical relevance.

Main Results:

Detailed overview of main ruminant APPs, their functions, and regulatory mechanisms.
Exploration of clinical applications in veterinary diagnostics and animal production.
Discussion of APP in small and wildlife ruminants and proteomic alterations.

Conclusions:

Ruminant APP are crucial biomarkers for health status and disease.
Understanding APP provides insights into physiological responses and aids in diagnostics.
Proteomic analysis enhances the detection and characterization of APP changes.