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Updated: May 23, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Myocardial viability imaging: does it still have a role in patient selection prior to coronary revascularisation?
Suchi Grover1, Govin Srinivasan, Joseph B Selvanayagam
1Department of Cardiovascular Medicine, Discipline of Medicine, Flinders University of South Australia, Flinders Medical Centre, Australia.
Insights
Myocardial viability testing helps guide revascularization in patients with severe left ventricular (LV) dysfunction and coronary artery disease (CAD). Further trials are needed to define its role in clinical outcomes.
Area of Science:
- Cardiology
- Medical Imaging
- Cardiac Surgery
Background:
- Patients with severe left ventricular (LV) dysfunction and multi-vessel coronary artery disease (CAD) face high risks during revascularization but may benefit most.
- Historically, assessing myocardial viability ('stunned' or 'hibernating' myocardium) has been crucial for revascularization decisions.
- Recent studies question the established role of viability testing in this high-risk patient group.
Purpose of the Study:
- To review the current position and optimal incorporation of myocardial viability testing in modern coronary revascularization strategies.
- To examine the role of available imaging modalities in assessing myocardial viability.
- To discuss the ongoing debate regarding the necessity of viability testing for revascularization decisions.
Main Methods:
- Literature review of recent studies and clinical trials.
- Analysis of the utility of various imaging modalities for viability assessment.
- Examination of the impact of viability testing on revascularization decision-making.
Main Results:
- Myocardial viability testing remains relevant for revascularization decisions in select patient populations.
- Current imaging modalities offer valuable insights into myocardial viability.
- The precise role and impact of viability testing on clinical outcomes require further investigation through large-scale randomized trials.
Conclusions:
- Myocardial viability testing continues to be an important factor in guiding revascularization strategies for patients with LV dysfunction and CAD.
- Further large-scale randomized trials focusing on clinical outcomes are essential to definitively establish the role of viability testing.
- Integrating viability assessment with other clinical factors is key in the modern era of coronary revascularization.
Abstract:
Patients with severe left ventricular (LV) dysfunction and multi-vessel coronary artery disease (CAD) are at high risk during revascularisation, however they are also likely to derive the most benefit. Historically, the detection of dysfunctional but potentially viable myocardium ('stunned or hibernating myocardium') has been central to the decision-making regarding revascularisation. A number of recent studies have challenged this paradigm, questioning the role of viability testing in this population. In this review, we will examine the position of viability testing and how it is best incorporated in the modern era of coronary revascularisation. We will outline the role of currently available imaging modalities in viability assessment. Myocardial viability testing will continue to play a role in revascularisation decisions, although larger randomised trials with clinical outcome end-points are needed to further define its role.
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