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Promoting drug discovery by collaborative innovation: a novel risk- and reward-sharing partnership between the German

Ruth Wellenreuther1, Dietrich Keppler, Dominik Mumberg

  • 1German Cancer Research Center (DKFZ) Heidelberg, Heidelberg, Germany.

Drug Discovery Today
|April 24, 2012
PubMed

Insights

Broad industry-academia partnerships are crucial for drug discovery amid rising healthcare costs. This review analyzes key factors for successful alliances, using a cancer research collaboration as a case study.

Area of Science:

  • Drug discovery and development
  • Biopharmaceutical industry
  • Academic research

Background:

  • Increasing cost pressures on healthcare systems necessitate innovative treatment paradigms.
  • Depletion of easily addressable targets in drug development requires novel approaches.
  • Public research institutions are increasingly expected to contribute to groundbreaking therapies.

Purpose of the Study:

  • To systematically analyze factors for successful industry-academia alliances in drug discovery.
  • To identify hurdles and best practices in setting up and managing such partnerships.
  • To evaluate the impact of these alliances on the drug discovery process.

Main Methods:

  • Systematic review of factors influencing industry-academia collaborations.
  • Case study analysis of the strategic alliance between the German Cancer Research Center and Bayer HealthCare.
  • Examination of goals, drivers, and challenges in collaborative drug development.

Main Results:

  • Broad partnerships are essential due to economic and scientific pressures.
  • Divergent goals and drivers between industry and academia present significant hurdles.
  • A systematic approach to alliance management is needed to maximize potential.

Conclusions:

  • Successful industry-academia alliances are vital for overcoming drug development challenges.
  • Addressing differing institutional goals is key to effective collaboration.
  • Strategic management of partnerships can significantly advance drug discovery.

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