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Updated: Aug 15, 2026

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
Published on: October 16, 2013
[Anesthesiologic implications in the Shy-Drager syndrome--a case report]
Abstract:
Based on a case report with vaginal hysterectomy, the anaesthetic implications are discussed in a patient with Shy-Drager syndrome, which is a degenerative disease in middle-aged to elderly patients, resulting in autonomic dysfunction. The syndrome is reviewed and the anaesthetic management is described. Adequate cardiovascular monitoring and maintenance of haemodynamic stability are important. The response to sympathomimetic drugs is unpredictable and may be extreme due to denervation hypersensitivity. In the postoperative period, signs of postural hypotension may be severe and require training by elevation of the upper part of the body, fluid therapy, sympathomimetics and fludrocortisone.
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