Rotational atherectomy: a "survivor" in the drug-eluting stent era
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Updated: May 23, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Marco Zimarino1, Thierry Corcos, Ezio Bramucci
1Institute of Cardiology and Center of Excellence on Aging, G. d'Annunzio University-Chieti, Italy. m.zimarino@unich.it
Abstract:
Mechanical debulking of coronary plaques with rotational atherectomy (RA) has been used for more than 20 years during percutaneous coronary interventions (PCI). Modification of plaque characteristics may be accomplished with selective ablation of inelastic fibrocalcific tissue. The use of RA, though reduced with the development of bare-metal stents (BMS) and even more with drug-eluting stents (DES), has never been completely abandoned. The present review will analyze reasons for conflicting results obtained in large series and randomized trials on this topic in the past, and will identify criteria for an appropriate use in current times.
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