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Updated: May 23, 2026

mirMachine: A One-Stop Shop for Plant miRNA Annotation
Published on: May 1, 2021
[Recent research progress of biogenesis and functions of miRNA*]
Sheng-Yun Ma1, Yu Bai, Ning Han
1Institution of Genetics, College of Life Science, Zhejiang University, Hangzhou 310058, China. mshy-052@163.com
Abstract:
MicroRNA*s are about 22nt noncoding RNAs, which are processed from precursors with a characteristic hairpin secondary structure in the biogenesis of microRNAs. Recently, miRNA* strands were shown to mediate post-transcriptional regulatory networks, rather than serve merely as non-functional by-product in general view. Unlike miRNAs bound to AGO1, miRNA* strands are bound to AGO2 to form RISC duplex to mediate RNAi, which is similar to siRNA. This paper mainly reviewed the recent research progresses on miRNA*, such as the biosynthesis, biological characteristics, and functions.
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