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A glycerin hydrogel-based wound dressing prevents peristomal infections after percutaneous endoscopic gastrostomy

Irina Blumenstein1, Dietmar Borger, Stefan Loitsch

  • 1First Medical Department, Johann Wolfgang Goethe-University Hospital, Frankfurt/Main, Germany.

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
|April 24, 2012
PubMed

Insights

A new glycerin hydrogel (GHG) dressing significantly reduced peristomal infections after percutaneous endoscopic gastrostomy (PEG). This novel wound care is a convenient, cost-effective alternative for PEG site management.

Area of Science:

  • Gastroenterology
  • Wound Care
  • Infectious Disease

Background:

  • Peristomal infection is a common complication following percutaneous endoscopic gastrostomy (PEG) despite antibiotic use.
  • A novel glycerin hydrogel (GHG) dressing shows potential for improved antimicrobial properties.
  • Larger trials are needed to validate the efficacy of GHG dressings for PEG-related infections.

Purpose of the Study:

  • To evaluate the superiority of glycerin hydrogel (GHG) dressings in reducing peristomal wound infections.
  • To compare the incidence of peristomal infections in patients receiving GHG versus traditional wound dressings over a 30-day follow-up period.

Main Methods:

  • A randomized controlled trial involving 68 cancer patients undergoing PEG.
  • Patients were assigned to either a glycerin hydrogel (GHG) group (n=34) or a traditional wound dressing group (n=34).
  • Infection assessment utilized two distinct scoring systems, with follow-up at specified intervals up to 4 weeks.

Main Results:

  • The GHG group showed a statistically significant reduction in mean infection scores at weeks 1 and 2 (P < .008 and P < .02, respectively).
  • Wound reactions were significantly lower in the GHG group (14.7%) compared to the traditional group (47.05%) after 7 days (P < .005).
  • GHG dressings required significantly fewer changes, reducing dressing frequency by fivefold.

Conclusions:

  • Glycerin hydrogel (GHG) wound dressings are effective in significantly reducing peristomal wound infections post-PEG.
  • GHG offers a convenient and cost-effective option for managing wounds associated with percutaneous endoscopic gastrostomy procedures.
Abstract

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