Related Experiment Video
Updated: May 23, 2026

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
Published on: July 1, 2018
Meningitis caused by Streptococcus suis: case report and review of the literature
Seong-Min Choi1, Bang-Hoon Cho, Kang-Ho Choi
1Department of Neurology, Chonnam National University Medical School, Gwangju, Korea.
Background:
Human infection with Streptococcus suis (S. suis), a zoonotic pathogen, has been reported mainly in pig-rearing and pork-consuming countries. Meningitis is the most-common clinical manifestation and is often associated with deafness and vestibular dysfunction.
Case Report:
A 57-year-old man was referred to the hospital with headaches, fevers, chills, and hearing impairment. Meningitis was confirmed and S. suis was isolated from the cerebrospinal fluid. Spondylodiscitis occurred after 2 weeks of antibiotic treatment, and was successfully treated with a prolonged course of antibiotics for another 4 weeks. His hearing loss was irreversible despite the improvement of other symptoms.
Conclusions:
We report the first human case of S. suis infection in Korea. In patients presenting with meningitis, S. suis should be considered if the characteristic features of prominent and early hearing loss are present.
Insights
Streptococcus suis (S. suis) infection can cause meningitis and hearing loss in humans. Early recognition of S. suis meningitis is crucial, especially with prominent hearing impairment, as seen in this Korean case.
Area of Science:
- Zoonotic infections
- Clinical microbiology
- Neurology
Background:
- Streptococcus suis (S. suis) is a zoonotic pathogen causing human infections, primarily in regions with pig farming and pork consumption.
- Meningitis is the most frequent clinical presentation of S. suis infection, often leading to permanent deafness and vestibular dysfunction.
Purpose of the Study:
- To report the first documented human case of Streptococcus suis infection in Korea.
- To highlight the clinical features and management of S. suis meningitis.
Main Methods:
- A case study of a 57-year-old male patient presenting with meningitis symptoms.
- Isolation of S. suis from cerebrospinal fluid.
- Treatment with antibiotics and monitoring for complications like spondylodiscitis.
Main Results:
- The patient was diagnosed with S. suis meningitis and subsequently developed spondylodiscitis.
- Successful treatment of spondylodiscitis with an extended antibiotic course.
- Irreversible hearing loss persisted despite clinical improvement in other symptoms.
Conclusions:
- This case represents the first human Streptococcus suis infection identified in Korea.
- Clinicians should consider S. suis in meningitis patients exhibiting early and significant hearing loss.
- Prompt diagnosis and appropriate antibiotic therapy are essential for managing S. suis infections, though hearing deficits may be permanent.
Related Concept Videos
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Viral Meningitis
Brain Abscess l: Introduction
Clinical Significance of Antibiotic Resistance
Encephalitis l: Introduction
