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Published on: September 16, 2022
Heterotopic ossification after cervical disc replacement: clinical significance and radiographic analysis. A
Patrick Guérin1, Ibrahim Obeid, Anouar Bourghli
1Department of Orthopaedic Surgery, University Hospital of Bordeaux, Bordeaux, France. pguerin_patrick@yahoo.fr
Insights
Heterotopic ossification (HO) is a common complication after cervical disc replacement (CDR) with the Mobi-C artificial disc, occurring in 27.7% of cases. This study found HO did not significantly impact clinical outcomes or range of motion (ROM).
Area of Science:
- Orthopedics
- Spinal Surgery
- Biomaterials
Background:
- Heterotopic ossification (HO) following cervical disc replacement (CDR) is not well-documented.
- Understanding HO incidence and risk factors after CDR is crucial for patient management.
Purpose of the Study:
- To determine the incidence of HO after Mobi-C CDR.
- To identify potential risk factors for HO development.
- To evaluate the impact of HO on clinical outcomes and range of motion (ROM).
Main Methods:
- Retrospective analysis of 71 patients undergoing Mobi-C CDR.
- Radiological evaluation for HO grading and ROM assessment at a mean 21-month follow-up.
Main Results:
- HO was detected in 23 treated segments (27.7%).
- Mean ROM increased from 8.1° preoperatively to 10.2° postoperatively.
- No significant correlation found between HO and clinical outcomes.
Conclusions:
- HO is a frequent occurrence after Mobi-C CDR.
- No specific risk factors were identified in this cohort.
- Further long-term studies are necessary to ascertain the clinical significance of HO.
Abstract:
Limited data is available regarding heterotopic ossification (HO) after cervical disc replacement (CDR). The goal of this study was to determine the incidence of HO after CDR with the Mobi-C artificial disc to identify the risk factors for HO, and to investigate whether HO affects clinical outcome and range of motion (ROM). Seventy one patients were included in this study. The mean follow-up was 21 months. Radiological evaluation included grading of HO and assessment of ROM for each level treated. HO was detectable in 23 treated segments (27.7%). The mean ROM was 8.1 degrees preoperatively and increased to 10.2 degrees at the last follow-up visit. Nevertheless, HO did not appear to affect clinical outcomes. HO appears to be a common complication after CDR. No specific risk factors have been clearly identified in our study. Long-term follow-up will be needed to assess the clinical significance of HO.
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