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Normal reticulin level in iliac bone marrow
1Department of Pathology, Ochsner Clinic, New Orleans, LA.
Archives of Pathology & Laboratory Medicine
|December 1, 1990
Summary
Normal bone marrow reticulin levels are low, with most patients falling into grades 0-1 on the Bauermeister scale. This finding is crucial for accurately diagnosing hematologic disorders.
Area of Science:
- Hematology
- Histopathology
Background:
- Reticulin staining is used to assess bone marrow fibrosis.
- Quantifying reticulin in normal bone marrow is essential for accurate diagnosis.
Purpose of the Study:
- To establish the normal range of reticulin in iliac bone marrow.
- To grade reticulin levels in hematologically normal individuals.
Main Methods:
- Bone biopsy specimens from 100 normal patients were analyzed.
- Reticulin stains were graded using the Bauermeister scale.
Main Results:
- The normal amount of marrow reticulin is low.
- 27% had grade 0, 42% grade N, 27% grade 1, and 4% grade 2.
- No patients exhibited grade 3 or 4 reticulin levels.
Conclusions:
- Establishing normal reticulin ranges is vital for diagnosing hematologic disorders.
- The Bauermeister scale provides a reliable method for grading reticulin.