Related Experiment Video
Updated: May 23, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Management of melanomas in children and young adults
Michelle Neier1, Alberto Pappo, Fariba Navid
1Valerie Fund Center, Goryeb Children's Hospital, Morristown, NJ 07962, USA. Michelle.Neier@atlantichealth.org
Insights
Pediatric melanoma, though rare, is increasing. This review covers childhood melanoma epidemiology, clinical presentation, diagnosis, and management strategies adapted from adult guidelines.
Area of Science:
- Dermatology
- Pediatric Oncology
Background:
- Melanoma incidence is rising in children and young adults.
- Understanding of pediatric melanoma etiology remains limited.
- Diagnosis can be challenging in pediatric cases.
Purpose of the Study:
- To review epidemiology, clinical presentation, staging, prognosis, and management of melanoma in pediatric populations.
- To consolidate current knowledge on childhood melanoma.
- To highlight the adaptation of adult treatment guidelines for pediatric melanoma.
Main Methods:
- Literature review of single-institution experiences and population-based analyses.
- Synthesis of data on pediatric melanoma.
- Analysis of current management and treatment protocols.
Main Results:
- Pediatric melanoma is uncommon but increasing.
- Clinical features are documented, but etiology is often unclear.
- Management relies on adult guidelines due to rarity.
Conclusions:
- Childhood melanoma requires specific consideration despite its rarity.
- Further research into pediatric melanoma etiology is needed.
- Current management strategies are based on adult protocols, necessitating careful application.
Abstract:
Melanoma is rare in children and young adults. The incidence is rising yearly in this population. The clinical features of the disease in the pediatric population have been well documented through single-institution experiences and population-based analyses. Still, our understanding of the etiologic factors in the majority of children remains unclear, and diagnosis of melanoma remains challenging in certain cases. Because of its rarity, the staging, management and treatment of melanoma in this population is adopted from adult guidelines. In this review, we provide information on the epidemiology, clinical presentation, staging, prognosis and management of melanoma in children and young adults.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Treatment Resistant Cancers

