Related Experiment Video
Updated: May 22, 2026

DNA-affinity-purified Chip (DAP-chip) Method to Determine Gene Targets for Bacterial Two component Regulatory Systems
Published on: July 21, 2014
Phylogenetic classification of diverse LysR-type transcriptional regulators of a model prokaryote Geobacter
Julia Krushkal1, Yanhua Qu, Derek R Lovley
1Department of Preventive Medicine, The University of Tennessee Health Science Center, Memphis, TN 38163, USA. krushkal@gmail.com
Abstract:
The protein family of LysR-type transcriptional regulators (LTTRs) is highly abundant among prokaryotes. We analyzed 10,145 non-redundant microbial sequences with homology to eight LysR family regulators of a model prokaryote, Geobacter sulfurreducens, and employed phylogenetic tree inference for LTTR classification. We also analyzed the arrangement of genome clusters containing G. sulfurreducens LTTR genes and searched for LTTR regulatory motifs, suggesting likely regulatory targets of G. sulfurreducens LTTRs. This is the first study to date providing a detailed classification of LTTRs in the deltaproteobacterial family Geobacteraceae.
More Related Videos
Related Concept Videos
Prokaryotic Transcriptional Activators and Repressors
Transcription of prokaryotic...
Prokaryotic Transcriptional Activators and Repressors
Transcription of prokaryotic...
Three-Domain System of Life
Prokaryotic Gene Structure and Organization
Diversity of Archaea III
Bacterial Transcription
Transcription can be divided into three main stages, each involving distinct DNA sequences to guide the polymerase. These are:

