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Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
Fetal growth restriction: current knowledge to the general Obs/Gyn
Luciano Marcondes Machado Nardozza1, Edward Araujo Júnior, Maurício Mendes Barbosa
1Department of Obstetrics, Federal University of São Paulo, São Paulo, Brazil. lunardozza@uol.com.br
Insights
Fetal growth restriction (FGR) affects 5-10% of pregnancies and is a leading cause of perinatal death. Early diagnosis and monitoring are crucial for managing FGR risks.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Medicine
- Fetal Medicine
Background:
- Fetal growth restriction (FGR) impacts 5-10% of pregnancies.
- FGR is the second leading cause of perinatal mortality.
- This review synthesizes current knowledge on FGR.
Purpose of the Study:
- To present recent knowledge on fetal growth restriction.
- To focus on FGR concept, etiology, classification, diagnosis, management, and prognosis.
Main Methods:
- Literature search conducted in PubMed, Embase, and Lilacs databases.
- Search term used: "fetal growth restriction".
Main Results:
- FGR classification includes type I (symmetric, early onset, proportional growth reduction, often chromosomal), type II (asymmetric, late onset, abdominal reduction, often placental insufficiency), and type III (mixed, early onset, infections/toxins).
- Diagnosis relies on clinical assessment, ultrasound, and Doppler studies for monitoring.
- No definitive treatment exists; optimal timing of pregnancy termination is critical.
Conclusions:
- Early FGR diagnosis is vital for etiological identification.
- Adequate monitoring of fetal vitality minimizes risks.
- Minimizing risks of prematurity and intrauterine hypoxia is essential.
Background:
Fetal growth restriction (FGR) is a condition that affects 5-10 % of gestations, and it is the second primary cause of perinatal mortality. In this review the most recent knowledge about FGR is presented focusing on its concept, etiology, classification, diagnosis, management, and prognosis.
Methods:
Searches were conducted in Pubmed, Embase and Lilacs database using the term fetal growth restriction.
Results:
FGR is classified as type I (symmetric), manifested early, in which there is a proportional reduction of all fetal parts, generally associated with chromosome abnormalities; type II (asymmetric), with late onset, in which there is a more accentuated reduction of the abdomen, generally related to placental insufficiency; and type III (mixed), with early manifestation, resulting from infections or exposure to toxic agents. Diagnosis may be clinical, although ultrasound associated with arterial and venous Doppler is essential for diagnosis and follow-up. Currently there is no treatment capable of controlling FGR, and the moment of interruption of pregnancy is of vital importance in order to protect maternal and fetal interests.
Conclusion:
Early diagnosis of FGR is very important, because it permits the etiological identification and adequate monitoring of fetal vitality, minimizing the risks related to prematurity and intrauterine hypoxia.
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