Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
Gastroesophageal Reflux Disease01:25

Gastroesophageal Reflux Disease

Gastroesophageal reflux disease (GERD) is the backward flow of stomach contents (acid, pepsin, or bile) into the esophagus, causing mucosal inflammation known as esophagitis. It results from failure of antireflux mechanisms, mainly the lower esophageal sphincter (LES), influenced by mechanical and physiological factors.Etiology and Risk FactorsGERD develops when LES function is weakened or when intra-abdominal pressure increases. Risk factors include aging, obesity, and sliding hiatal hernia,...
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical Septal Myectomy and Atrial Myxoma Resection: Two Diseases, One Heart, and a Case Report.

The American journal of case reports·2026
Same author

Effects of SGLT2 inhibitor dapagliflozin on the heart of rats with long-standing Type 1 diabetes mellitus: Protein profile.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

Liraglutide Modifies Gut Microbiota Without Modulating Doxorubicin-Induced Toxicity in Rats.

Antioxidants (Basel, Switzerland)·2026
Same author

Septic Cardiac Remodeling: A New Concept in Cardiac Dysfunction Induced by Experimental Sepsis.

Antioxidants (Basel, Switzerland)·2026
Same author

Effects of Early Treatment with Lipid Core Nanoparticles-Associated Methotrexate on Cardiac Remodeling and Soleus Muscle Inflammasomes in Infarcted Rats.

International journal of molecular sciences·2026
Same author

Influence of Bean Flour (<i>Phaseolus vulgaris</i>) on Cardiac Remodeling after Acute Myocardial Infarction in Rats.

Journal of medicinal food·2025

Related Experiment Videos

Gastrointestinal changes associated to heart failure.

Fernando G Romeiro1, Katashi Okoshi, Leonardo A M Zornoff

  • 1Faculdade de Medicina de Botucatu, SP, Brazil.

Arquivos Brasileiros De Cardiologia
|April 25, 2012
PubMed
Summary

Chronic heart failure causes gastrointestinal changes like mucosal edema and bacterial overgrowth. These digestive issues worsen heart failure by leading to cachexia, inflammation, and anemia.

Related Experiment Videos

Area of Science:

  • Gastroenterology
  • Cardiology
  • Internal Medicine

Background:

  • Chronic heart failure (CHF) is linked to significant gastrointestinal (GI) alterations.
  • These GI changes can negatively impact patient outcomes and disease progression.

Purpose of the Study:

  • To review the pathophysiology and clinical consequences of GI abnormalities in heart failure patients.
  • To highlight the importance of understanding these digestive changes for managing CHF.

Main Methods:

  • Literature review of studies on gastrointestinal changes in chronic heart failure.
  • Analysis of structural and functional GI abnormalities and their clinical sequelae.

Main Results:

  • Identified GI abnormalities include absorptive mucosa edema and intestinal bacterial overgrowth.
  • Clinical consequences encompass cardiac cachexia, systemic inflammation, and anemia.
  • These conditions can exacerbate ventricular dysfunction.

Conclusions:

  • Understanding GI changes is crucial for preventing and managing systemic consequences of heart failure.
  • Currently, no specific therapies target GI issues in heart failure, emphasizing the need for further research.