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Infliximab (Remicade) and increased incidence of development of basal cell carcinoma

Elizabeth Gaines-Cardone1, Elizabeth K Hale

  • 1SUNY Downstate Department of Dermatology, Brooklyn, NY, USA.

Journal of Drugs in Dermatology : JDD
|April 25, 2012
PubMed

Immunosuppression is a known risk factor for the development of non-melanoma skin cancers (NMSC). Certain medications that induce immunosuppression, such as tumor necrosis factor-α (TNF-α) inhibitors, are being used more frequently. We report a case of a young, pregnant woman who was treated with infliximab for Crohn's disease, and subsequently experienced a rapid growth of two pre-existing basal cell carcinomas. As use of TNF-α inhibitors increases, it is important to closely monitor patients for the development of NMSC.

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