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Related Experiment Video

Updated: May 22, 2026

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Published on: September 5, 2013

Multiplex molecular analysis of CTCs.

Anieta M Sieuwerts¹, Stefanie S Jeffrey

¹Department of Translational Cancer Genomics and Proteomics, Erasmus Medical Center, Rotterdam, The Netherlands.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer

|April 25, 2012

Summary

Characterizing circulating tumor cells (CTCs) aids in selecting cancer therapies. The MagSweeper technology isolates pure CTCs for molecular analysis, enabling personalized cancer care.

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Published on: October 23, 2011

Area of Science:

Oncology
Molecular Biology
Biotechnology

Background:

Circulating tumor cells (CTCs) are crucial biomarkers in cancer.
Characterizing CTCs aids in personalized therapeutic selection for cancer patients.
Multiplex analysis of CTCs requires robust isolation techniques.

Purpose of the Study:

To discuss molecular profiling of enriched CTCs.
To introduce the MagSweeper technology for CTC isolation.
To highlight the applicability of discussed methods for multiplex CTC analysis.

Main Methods:

Focus on molecular profiling of CTCs post-enrichment.
Description of the MagSweeper technology for isolating live, purified CTCs.
Discussion applicable to various multiplex analysis techniques for CTCs.

Main Results:

MagSweeper technology enables isolation of live and highly purified CTCs.
Isolated CTCs can be used for pooled or single-cell molecular analyses.
The technology supports in vitro or in vivo CTC growth.

Conclusions:

Molecular profiling of CTCs is vital for personalized cancer therapy.
The MagSweeper technology offers a method for high-purity CTC isolation.
The principles discussed apply broadly to multiplex CTC analysis, regardless of enrichment method.