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Hyperuricemia: a reality in the Indian obese
Carlyne Remedios1, Miloni Shah, Aparna Govil Bhasker
1Centre for Obesity and Diabetes Surgery, H. Goregaonkar Road, Mumbai, India. carlyne@codsindia.com
Obesity Surgery
|April 25, 2012
Summary
Hyperuricemia is common in the Indian obese population, affecting 44.6%. This study found hyperuricemia is linked to hypertension but not type 2 diabetes or dyslipidemia in obese individuals.
Area of Science:
- Endocrinology
- Metabolic Syndrome Research
- Obesity Studies
Background:
- Hyperuricemia is frequently linked to obesity and metabolic syndrome.
- Understanding its prevalence in specific populations is crucial for public health.
- The Indian obese population's hyperuricemia status requires detailed investigation.
Purpose of the Study:
- To determine the prevalence of hyperuricemia in Indian obese patients.
- To investigate correlations between hyperuricemia, body mass index (BMI), waist circumference, and metabolic syndrome components.
- To analyze gender-specific incidence of hyperuricemia in this cohort.
Main Methods:
- Retrospective observational study design.
- Inclusion of 409 obese patients.
- Measurement of serum uric acid levels, anthropometric parameters, and recording of comorbidities like type 2 diabetes mellitus (T2DM), hypertension, and dyslipidemia.
Main Results:
- Overall hyperuricemia prevalence was 44.6% in the Indian obese population.
- Higher BMI correlated with increased hyperuricemia incidence (47% in BMI >35 kg/m²).
- Hyperuricemia was significantly more common in males (50%) than females (21.7%) and strongly associated with hypertension (47.3%).
Conclusions:
- The Indian obese population exhibits a high prevalence of hyperuricemia, particularly in males.
- Hyperuricemia shows a significant association with hypertension.
- No significant correlation was found between hyperuricemia and type 2 diabetes mellitus or dyslipidemia in this study group.
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