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Updated: May 22, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Early predictors of obesity and cardiovascular risk among American Indian children
Sara M Lindberg1, Alexandra K Adams, Ronald J Prince
1UW Center for Women's Health and Health Disparities Research, University of Wisconsin-Madison, 310 N. Midvale Blvd., Suite 201, Madison, WI 53705, USA. smlindberg@wisc.edu
Insights
American Indian children face high obesity rates. Key factors like excess weight gain during pregnancy and early breastfeeding cessation significantly impact a child's body mass index (BMI) within the first year of life, influencing later health outcomes.
Area of Science:
- Pediatric obesity
- Cardiovascular health in children
- American Indian health disparities
Background:
- American Indian (AI) children exhibit the highest obesity rates in the U.S., with increasing trends.
- Childhood obesity is linked to adverse cardiovascular risk markers.
- Understanding early life determinants is crucial for intervention.
Purpose of the Study:
- To investigate prenatal and early postnatal factors influencing body mass index (BMI) trajectories in AI children.
- To examine the impact of early life factors on adiposity and cardiovascular risk markers.
- To identify critical periods for intervention in AI children's weight management.
Main Methods:
- Screening of 471 AI children (ages 5-8) from three Wisconsin tribes.
- Collection of anthropometric, body fat, lipid, and glucose data.
- Utilized tribal WIC records and clinic charts for BMI trajectories, maternal, and feeding environment data.
Main Results:
- 47% of children were overweight or obese.
- Childhood BMI category was primarily established within the first year of life.
- Macrosomia, excess gestational weight gain, and early breastfeeding cessation predicted BMI at age 1.
- Overweight/obesity at age 1 correlated with higher adiposity and LDL cholesterol at ages 5-8.
Conclusions:
- Early postnatal factors, including maternal weight gain and breastfeeding duration, significantly shape infant BMI.
- Infant BMI at age 1 is a strong predictor of cardiovascular risk markers in early childhood.
- Targeting the first year of life is critical for preventing obesity and cardiovascular risks in AI children.
Abstract:
American Indian (AI) children have the highest rates of obesity among ethnic groups in the United States, and rates continue to increase. This study was designed to examine the effects of prenatal and early postnatal factors on AI children's body mass index (BMI) trajectories, adiposity, and cardiovascular risk markers during early childhood. We screened 471 AI children (ages 5-8) from three Wisconsin tribes. Screenings included anthropometric and body fat measures and non-fasting lipid and glucose via fingerstick blood samples. Tribal records from Women Infants and Children (WIC) programs and clinic charts provided data on children's BMI trajectories, maternal prenatal factors, and the early postnatal feeding environment. Forty-seven percent of children were overweight or obese. Analysis of growth trajectories showed that children's BMI category was largely determined within the 1 year of life. Significant predictors of children's BMI category at age 1 included macrosomia (OR 4.38), excess gestational weight gain (OR 1.64) and early termination of breastfeeding (OR 1.66). Children who were overweight/obese at age 1 had greater odds of being overweight (OR 3.42) or obese (OR 3.36), and having unhealthy levels of body fat (OR 2.95) and LDL cholesterol (OR 1.64) at ages 5-8. Children's BMI category is determined in the early post-natal environment, within the 1 year of life, by factors including excess gestational weight gain and early termination of breastfeeding. In turn, children's BMI category at age 1 predicts the emergence of cardiovascular risk markers in early childhood.
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