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An implanted peritoneal oxygen tonometer that can be calibrated in situ
R B Spokane1, L C Clark, H K Bhargava
1Department of Neurophysiology, Children's Hospital Research Foundation, Cincinnati, Ohio 45229-2899.
ASAIO Transactions
|July 1, 1990
Summary
This study measured peritoneal oxygen tension in rabbits using a novel Silastic tonometer. The device allowed continuous monitoring under various conditions, providing insights into abdominal oxygen levels.
Area of Science:
- Physiology
- Biomedical Engineering
Background:
- Accurate measurement of peritoneal oxygen tension is crucial for understanding abdominal physiological conditions.
- Existing methods for monitoring oxygen levels in the peritoneal cavity have limitations.
Purpose of the Study:
- To develop and evaluate a novel tonometer for continuous measurement of peritoneal oxygen tension.
- To assess peritoneal oxygen tension in rabbits under different physiological states and breathing conditions.
Main Methods:
- A Silastic tonometer with an integrated oxygen electrode was developed for implantation.
- The tonometer system included tubes for gas-equilibrated electrolyte solution and remote kinetic calibration.
- Peritoneal oxygen tension was continuously monitored in six rabbits, both awake and anesthetized.
Main Results:
- The Silastic tonometer enabled continuous and reliable measurement of peritoneal oxygen tension.
- Peritoneal oxygen tension varied under different oxygen breathing conditions in both awake and anesthetized rabbits.
- The system demonstrated feasibility for in-vivo monitoring.
Conclusions:
- The developed Silastic tonometer is a viable tool for continuous peritoneal oxygen tension monitoring.
- This technology can facilitate further research into peritoneal oxygen dynamics.
- Understanding peritoneal oxygen levels is important for various clinical and research applications.