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Updated: May 22, 2026
04:11
Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
Published on: December 15, 2023
Hepatitis B virus infection and pregnancy: a practical approach
1Department of Gastroenterology and Hepatology, Sir Ganga Ram Hospital, New Delhi 110 060, India. ashishk10@yahoo.com
Summary
Hepatitis B virus (HBV) infection management during pregnancy is crucial for preventing mother-to-child transmission (MTCT). This review offers practical strategies to address the unique challenges of HBV in pregnant individuals.
Area of Science:
- Hepatology
- Infectious Diseases
- Maternal-Fetal Medicine
Background:
- Hepatitis B virus (HBV) infection is a significant global health concern, with 350 million chronic carriers worldwide.
- Over 50% of chronic HBV infections stem from mother-to-child transmission (MTCT), often resulting in lifelong illness due to immune tolerance.
- Chronic HBV in pregnancy poses unique challenges due to complex physiological and pathophysiological interactions.
Purpose of the Study:
- To provide a practical approach for managing chronic Hepatitis B virus infection in pregnant individuals.
- To outline strategies for preventing mother-to-child transmission of HBV.
- To address the clinical issues arising from varied patient presentations during pregnancy.
Main Methods:
- This review synthesizes current knowledge on HBV infection in pregnancy.
- It examines the interplay between pregnancy physiology and HBV pathophysiology.
- The focus is on practical management and prevention strategies.
Main Results:
- Management of chronic HBV during pregnancy is essential for controlling global HBV infection rates.
- Preventing MTCT of HBV is critical for reducing long-term morbidity and mortality.
- Understanding the varied clinical presentations is key to successful maternal and fetal outcomes.
Conclusions:
- Effective management of chronic HBV in pregnancy is vital for preventing mother-to-child transmission.
- Addressing the complex interactions between pregnancy and HBV infection is necessary for optimal outcomes.
- This review provides a practical framework for clinicians managing HBV in pregnant patients.
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