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Related Concept Videos

Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Endotracheal Tube Extubation01:24

Endotracheal Tube Extubation

Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals.

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Related Experiment Video

Updated: Jul 10, 2026

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
09:17

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness

Published on: May 2, 2017

Long term survival after intensive care.

S Ridley1, R Jackson, J Findlay

  • 1Anaesthetic Department, Western Infirmary, Glasgow.

BMJ (Clinical Research Ed.)
|November 17, 1990
PubMed
Summary

Long-term survival in intensive therapy units depends on patient age and illness severity. Elderly patients and those with severe conditions face poorer outcomes, highlighting critical care needs.

Area of Science:

  • Critical Care Medicine
  • Intensive Care Unit (ICU) Outcomes
  • Prognostic Factor Analysis

Background:

  • Critically ill patients admitted to intensive therapy units (ITUs) have varying long-term survival rates.
  • Understanding factors influencing survival is crucial for improving patient management and outcomes.

Purpose of the Study:

  • To investigate the long-term survival of patients admitted to an intensive therapy unit.
  • To determine the impact of age, illness severity (APACHE II score), and diagnostic category on survival.
  • To identify independent prognostic factors for long-term outcomes in critically ill adults.

Main Methods:

  • Retrospective observational study utilizing prospectively gathered data from a regional intensive therapy unit.
  • Inclusion of 497 critically ill adult patients with complete Acute Physiology and Chronic Health Evaluation (APACHE) II scores.
Keywords:
Professional Patient Relationship

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Last Updated: Jul 10, 2026

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  • Data collection on age, APACHE II score, diagnostic category, in-unit mortality, and long-term survival post-discharge.
  • Main Results:

    • Overall, 52% of patients survived to two years post-admission.
    • Higher APACHE II scores (≥20) and older age (≥65 years) were significantly associated with lower one-year survival rates.
    • Diagnostic category influenced survival, with trauma victims having better outcomes than those with gastrointestinal pathology; however, only age and severity of illness were independent prognostic factors.

    Conclusions:

    • Long-term survival in intensive therapy units is significantly influenced by the severity of illness and patient age.
    • The elderly population admitted to ITUs experiences a particularly poor prognosis.
    • Age and illness severity are key independent predictors of long-term survival following intensive care.