Related Experiment Video

Updated: May 22, 2026

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography
06:44

Deep Vein Thrombosis Induced by Stasis in Mice Monitored by High Frequency Ultrasonography

Published on: April 13, 2018

Recurrent deep venous thrombosis in an HIV-positive and injecting drug user woman

Vitorino Modesto Dos Santos1, Ludmila Thommen Teles, Carlos Eduardo Silva Leão

  • 1Department of Internal Medicine, Catholic University (UCB), Brasília-DF, Brazil.

Indian Journal of Sexually Transmitted Diseases and AIDS
|April 25, 2012
PubMed

Insights

This case study highlights recurrent deep venous thrombosis (DVT) in an HIV-infected intravenous drug user. It emphasizes the risks of groin injections and the link between HIV and venous thromboembolism.

Area of Science:

  • Vascular Medicine
  • Infectious Diseases
  • Cardiology

Background:

  • Deep venous thrombosis (DVT) is a significant health concern, particularly in specific patient populations.
  • Intravenous drug use (IDU) and Human Immunodeficiency Virus (HIV) infection are known risk factors for thromboembolic events.
  • Understanding the anatomical sites of drug injection is crucial for identifying potential vascular complications.

Observation:

  • A 44-year-old female with a history of IDU and HIV presented with recurrent DVT.
  • She reported injecting cocaine into the groin and dorsal foot veins, leading to multiple lower limb DVT episodes and soft-tissue infections.
  • Doppler ultrasound revealed right popliteal vein thrombosis with partial recanalization and calcified thrombi in the right femoral vein.

Findings:

  • The patient experienced recurrent episodes of deep venous thrombosis and soft-tissue infections.
  • Diagnostic imaging confirmed thrombosis in the popliteal vein and calcified thrombi in the femoral vein.
  • Treatment with heparin and oral anticoagulation resulted in an uneventful clinical course and asymptomatic discharge.

Implications:

  • This case underscores the critical need for increased awareness regarding the risks associated with injecting drugs into the groin and superficial femoral veins, which are integral to the deep venous system.
  • The association between HIV infection and an increased risk of venous thrombosis is highlighted.
  • Clinicians should consider DVT in HIV-infected individuals with a history of intravenous drug use, especially with lower limb symptoms.

Keywords:
Antiretroviral treatmentHIV/AIDSintravenous drug usethrombosis

More Related Videos

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture11:14

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Published on: October 12, 2018

Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...