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Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
Published on: February 8, 2020
Cervical lymph node metastasis in renal cell carcinoma.
Mahmut Ozkiriş1, Utku Kubilay, Ozan Seymen Sezen
1Department of Otolaryngology, Head and Neck Surgery, Kayseri Tekden Hospital, Kayseri, Turkey.
Journal of Oral and Maxillofacial Pathology : JOMFP
|April 25, 2012
Summary
Renal cell carcinoma (RCC) rarely presents as a head and neck mass, though it is a common site for metastasis. Surgical excision is recommended for these rare presentations to improve patient quality of life.
Area of Science:
- Oncology
- Head and Neck Surgery
Background:
- Renal cell carcinoma (RCC) accounts for 3% of adult malignancies.
- RCC typically affects individuals in their fifth and sixth decades, with a 1.5:1 male-to-female ratio.
Observation:
- Head and neck metastases are the third most common metastatic site for primary tumors below the clavicle.
- While 7.5% of RCC patients present with head and neck metastasis, only 1% have metastases confined to this region.
- Solitary cervical metastatic masses from RCC are exceptionally rare.
Findings:
- Head and neck metastasis can be the initial presenting symptom of renal cell carcinoma.
- Surgical intervention is often the preferred treatment for head and neck metastases of RCC.
Implications:
- Renal cell carcinoma should be included in the differential diagnosis for unexplained head and neck lesions.
- Addressing head and neck metastases promptly is crucial for managing morbidity and enhancing patient quality of life.
