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Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Development of Human Microbiota01:30

Development of Human Microbiota

The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...

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Related Experiment Video

Updated: May 22, 2026

Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis
07:34

Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis

Published on: April 16, 2019

Pyuria in institutionalized elderly subjects.

K Rodgers1, L Nicolle, M McIntyre

  • 1Sections of Geriatric Medicine and Infectious Diseases, Department of Internal Medicine and Department of Medical Microbiology, University of Manitoba; and Deer Lodge Centre, Winnipeg, Manitoba.

The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses
|April 25, 2012
PubMed
Summary
This summary is machine-generated.

In institutionalized elderly, pyuria (white blood cells in urine) is common and often linked to bacteriuria (bacteria in urine). However, pyuria also frequently occurs without bacteriuria, requiring further clinical evaluation.

Keywords:
ElderlyPyuriaUrinalysisUrinary infection

Related Experiment Videos

Last Updated: May 22, 2026

Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis
07:34

Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis

Published on: April 16, 2019

Area of Science:

  • Geriatric Medicine
  • Infectious Diseases
  • Clinical Pathology

Background:

  • Urinary tract infections are common in institutionalized elderly.
  • Pyuria and bacteriuria are key indicators but their relationship in this population needs clarification.

Purpose of the Study:

  • To investigate the prevalence and significance of pyuria in institutionalized elderly residents.
  • To assess the association between pyuria, bacteriuria, and urinalysis parameters.

Main Methods:

  • Analysis of 243 urine specimens from 76 elderly residents.
  • Urine culture, quantitative leukocyte count, and urinalysis were performed.
  • Leukocyte esterase test was evaluated for diagnostic accuracy.

Main Results:

  • Significant bacteriuria found in 63% of specimens; pyuria in 88%.
  • Pyuria was present in most cases of bacteriuria (single and multiple organisms) and also in 80% of non-bacteriuric specimens.
  • Leukocyte esterase test showed high positive predictive value (99%) but low negative predictive value (30%) for pyuria.
  • Quantitative pyuria correlated with proteinuria and inversely with pH.
  • Persistent pyuria levels were observed in individuals with persistent bacteriuria.

Conclusions:

  • Pyuria is highly prevalent in institutionalized elderly and significantly associated with bacteriuria.
  • However, pyuria is also common in the absence of bacteriuria, highlighting the need for careful clinical interpretation.
  • The clinical significance of pyuria in this demographic warrants further investigation.