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Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
Published on: August 8, 2025
Primary hepatic benign schwannoma.
Michihiro Hayashi1, Atsushi Takeshita, Kazuhiro Yamamoto
1Michihiro Hayashi, Nobuhiko Tanigawa, Department of General and Gastroenterological Surgery, Department of Pathology, Department of Radiology, Osaka Medical College Hospital, 2-7 Daigaku-machi, Takatsuki City, Osaka 569-8686, Japan.
World Journal of Gastrointestinal Surgery
|April 25, 2012
Summary
A rare benign liver tumor, hepatic schwannoma, was identified in a patient. This case highlights the diagnostic challenges of small, primary liver schwannomas.
Area of Science:
- Hepatology
- Surgical Pathology
- Oncology
Background:
- Schwannomas are typically benign neoplasms arising from Schwann cells of peripheral nerves.
- Primary hepatic schwannomas are exceptionally rare, posing diagnostic challenges.
- This case presents a small hepatic schwannoma in a patient with a history of gastrointestinal stromal tumor.
Purpose of the Study:
- To report an extremely rare case of primary hepatic schwannoma.
- To discuss the diagnostic difficulties associated with small hepatic schwannomas.
- To emphasize the importance of considering hepatic schwannoma in the differential diagnosis of liver tumors.
Main Methods:
- A 64-year-old male patient with a history of resected gastrointestinal stromal tumor (GIST) presented with a liver lesion.
- The patient underwent lateral segmentectomy of the liver.
- Histopathological examination and immunohistochemistry (S-100 protein, c-kit, CD34) were performed.
Main Results:
- Histopathology confirmed a benign hepatic schwannoma, measuring 23mm.
- Immunohistochemistry showed positive staining for S-100 protein and negative for c-kit and CD34.
- This represents one of the smallest reported cases of primary hepatic schwannoma.
Conclusions:
- Primary hepatic schwannoma is a rare entity that can mimic metastatic disease.
- Preoperative diagnosis of small hepatic schwannomas is challenging.
- Hepatic schwannoma should be included in the differential diagnosis of liver tumors with benign clinical characteristics.
