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Updated: May 22, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Bacteruria with group-B streptococcus: is it a risk factor for adverse pregnancy outcomes?
Roy Kessous1, Adi Y Weintraub, Ruslan Sergienko
1Department of Obstetrics and Gynecology, Soroka University Medical Center, Beer-Sheva, Israel. kessousr@bgu.ac.il
Objective:
To investigate pregnancy outcomes of patients with and without group-B streptococcus (GBS) bacteriuria.
Methods:
A retrospective study comparing pregnancy outcomes of women with GBS bacteriuria during pregnancy, those with positive GBS vaginal cultures and those without GBS colonization during pregnancy was conducted.
Results:
A significant linear association was found with regard to intrapartum fever (U-GBS 0.5%, V-GBS 0.3%, no GBS 0.1%, p = 0.001) and chorioamnionitis (U-GBS 3.3%, V-GBS 1%, no GBS 0.7%, p = 0.001). In addition preterm delivery (15.3% vs. 7.9%, p = 0.001) and premature rupture of membranes (10.7% vs. 7.9, p = 0.001) were significantly higher in the U-GBS group compared to no GBS. Woman with U-GBS had higher rates of diabetes mellitus, hypertensive disorders, and habitual abortions as well as a higher risk for intrauterine growth restriction (IUGR). In addition patients with U-GBS underwent induction of labor and cesarean delivery more frequently.
Conclusions:
Our study showed a significant association between U-GBS and adverse obstetrical outcomes. In addition a linear association was found between GBS culture location and obstetric complications. However, GBS was not associated with adverse perinatal outcome in our population.
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