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[A child with convulsions of unknown origin: posterior reversible encephalopathy syndrome]

Bart Grimminck1, Huib de Jong, Menno Sluzewski

  • 1St. Elisabeth Ziekenhuis, Tilburg, Afd. Kindergeneeskunde, the Netherlands.

Nederlands Tijdschrift Voor Geneeskunde
|April 26, 2012
PubMed

Insights

Posterior reversible encephalopathy syndrome (PRES), a rare complication of post-streptococcal glomerulonephritis (PSGN), can occur in children. Early recognition and treatment of PRES in children with PSGN are crucial for preventing neurological damage.

Area of Science:

  • Pediatric Neurology
  • Nephrology
  • Infectious Diseases

Background:

  • Posterior reversible encephalopathy syndrome (PRES) is a rare neurological complication.
  • Post-streptococcal glomerulonephritis (PSGN) is a common sequela of streptococcal infections in children.

Observation:

  • An 8-year-old boy presented with seizures, headache, vomiting, hypertension, and periorbital edema.
  • Investigations revealed proteinuria, hematuria, and intracranial abnormalities.
  • A history of recent streptococcal tonsillitis treated with amoxicillin was noted.

Findings:

  • The patient was diagnosed with PRES secondary to PSGN.
  • Successful treatment with anticonvulsants and antihypertensives led to complete recovery.
  • This case highlights the link between PSGN and PRES in pediatric patients.

Implications:

  • Early diagnosis and prompt management of PRES in children with PSGN are vital.
  • Effective treatment can prevent severe neurological sequelae and mortality.
  • This case underscores the importance of considering PRES in children presenting with neurological symptoms post-infection.
Abstract

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