Meningioma with hemorrhagic onset: two case reports

Area of Science:

• Neurology
• Neurosurgery
• Oncology

Background:

• Meningiomas are typically benign tumors arising from the meninges.
• Hemorrhage is an uncommon but significant complication of meningiomas, potentially occurring spontaneously or due to medical interventions.
• The pathophysiology of intratumoral hemorrhage in meningiomas is not fully understood.

Observation:

• Two cases of meningioma with intratumoral hemorrhage are presented: a 16-year-old male with an angiomatous meningioma presenting with neurological deficits and a 45-year-old female with a meningothelial meningioma presenting with sudden neurological decline.
• Magnetic Resonance Imaging (MRI) was instrumental in diagnosing the lesions and associated bleeding in both cases.
• Surgical intervention was performed in both cases, with intraoperative confirmation of intratumoral bleeding.

Findings:

• The first patient's tumor was identified as an angiomatous meningioma with hemorrhage, while the second patient's was a meningothelial meningioma with hemorrhage.
• These cases highlight the diverse histological types of meningiomas that can present with bleeding.
• The clinical presentation varied, emphasizing the need for high suspicion in cases of sudden neurological deterioration.

Implications:

• Hemorrhagic onset of meningiomas, though rare, necessitates prompt diagnosis and management.
• Effective prevention and improved outcomes for patients with intratumoral hemorrhage depend on timely diagnosis and appropriate treatment strategies.
• Further research into the mechanisms of meningioma hemorrhage may lead to improved preventative measures and therapeutic approaches.