Related Experiment Video

Updated: May 22, 2026

Induction and Monitoring of Active Delayed Type Hypersensitivity (DTH) in Rats
13:26

Induction and Monitoring of Active Delayed Type Hypersensitivity (DTH) in Rats

Published on: July 19, 2007

Data on Wistar Hannover rats from an immunotoxicity study

Hideyuki Yamatoya1, Hiroaki Kawaguchi, Takeshi Fukuda

  • 1The United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi 753-8515, Japan.

Experimental Animals
|April 26, 2012
PubMed
Summary

This study tracked rat immune system development, finding sex differences in cell counts and antibody production. These immunological insights aid in evaluating drug-induced immune toxicity in Wistar Hannover rats.

More Related Videos

Induction and Monitoring of Adoptive Delayed-Type Hypersensitivity in Rats22:06

Induction and Monitoring of Adoptive Delayed-Type Hypersensitivity in Rats

Published on: October 1, 2007

Gap Junctional Intercellular Communication: A Functional Biomarker to Assess Adverse Effects of Toxicants and Toxins, and Health Benefits of Natural Products05:27

Gap Junctional Intercellular Communication: A Functional Biomarker to Assess Adverse Effects of Toxicants and Toxins, and Health Benefits of Natural Products

Published on: December 25, 2016

Related Concept Videos

Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...